Name: IL-1 Beta Rabbit Polyclonal antibody
Brand: Proteintech

Tested Applications

Applications:

WB, IHC, IF, ELISA
Application not tested? Please see our Guarantee

THP-1 cells were subjected to SDS PAGE followed by western blot with 16806-1-AP (IL1 beta antibody) at dilution of 1:1000 incubated at room temperature for 1.5 hours.

Species specificity:

human, zebrafish

Positive WB detected in:

THP-1 cells, human adrenal gland tissue, A431 cells

Recommended dilution:

WB : 1:500-1:2000

Product Information

Source:

Rabbit

Purification method:

Antigen affinity purification

Isotype:

IgG

Storage:

PBS with 0.02% sodium azide and 50% glycerol pH 7.3.
Store at -20°C. Stable for one year after shipment. Aliquoting is unnecessary for -20^oC storage.

Immunogen Information

Immunogen:

IL-1 Beta fusion protein Ag10295

Full name:

interleukin 1, beta

Calculated molecular weight:

269 aa, 31 kDa

Observed molecular weight:

30-35 kDa

GenBank accession number:

BC008678

Gene ID (NCBI):

3553

Gene symbol

IL1B

Synonyms

IL1 beta, Catabolin, IL 1, IL 1 beta, IL1 BETA, IL-1 beta, IL1- beta, IL1B, IL1beta, IL1F2, IL-1β, Interleukin 1 beta, interleukin 1, beta, Pro IL-1β

Background

Interleukin-1, produced mainly by blood monocytes, mediates the panoply of host reactions collectively known as acute phase response. It is identical to endogenous pyrogen. The multiple biologic activities that define IL1 are properties of a 15- to 18-kD protein that is derived from a 30- to 35-kD precursor. Interleukin 1β (IL-1B) is a member of the interleukin 1 cytokine family. It is a pro-inflammatory cytokine against infection, playing an important role in the pathogenesis of cancers. It signals through various adaptor proteins and kinases that lead to activation of numerous downstream targets. The expression level of IL-1B is very low.

Showing 1- [6] of [192] Publications

Author:		Yifan Jia
Pubmed ID:		30581532
Journal:		Oxid Med Cell Longev
Title:		Methane-Rich Saline Ameliorates Sepsis-Induced Acute Kidney Injury through Anti-Inflammation, Antioxidative, and Antiapoptosis Effects by Regulating Endoplasmic Reticulum Stress.
Application:		IHC

Species:		mouse

Author:		Chunhui Sun
Pubmed ID:		30585631
Journal:		J Cell Physiol
Title:		Purple sweet potato color attenuated NLRP3 inflammasome by inducing autophagy to delay endothelial senescence.
Application:		WB

Species:		mouse

Author:		Jingxin Mao
Pubmed ID:		30618760
Journal:		Front Pharmacol
Title:		Protective Effects of Costunolide Against D-Galactosamine and Lipopolysaccharide-Induced Acute Liver Injury in Mice.
Application:		WB

Species:		mouse

Author:		Yutong He
Pubmed ID:		30641432
Journal:		Int Immunopharmacol
Title:		Hepatoprotective effects and structure-activity relationship of five flavonoids against lipopolysaccharide/d-galactosamine induced acute liver failure in mice.
Application:		WB

Species:		mouse

Author:		Hong Li
Pubmed ID:		30651860
Journal:		Exp Ther Med
Title:		Relationship between serum IL-1β and insomnia and liver depression in patients with perimenopausal non-organic sleep disorder.
Application:		WB

Species:

Author:		Ruslan Rafikov
Pubmed ID:		30652485
Journal:		Antioxid Redox Signal
Title:		GENDER DIFFERENCE IN DAMAGE MEDIATED SIGNALING CONTRIBUTES TO PULMONARY ARTERIAL HYPERTENSION.
Application:		WB

Species:		rat

WB Figures

A431 cells were subjected to SDS PAGE followed by western blot with 16806-1-AP (IL1 beta antibody at dilution of 1:600 incubated at room temperature for 1.5 hours.

WB analysis of human adrenal gland using 16806-1-AP

human adrenal gland tissue were subjected to SDS PAGE followed by western blot with 16806-1-AP (IL1 beta antibody) at dilution of 1:100 incubated at room temperature for 1.5 hours.

THP-1 cells were subjected to SDS PAGE followed by western blot with 16806-1-AP (IL1 beta antibody) at dilution of 1:1000 incubated at room temperature for 1.5 hours.

IHC Figures

IHC staining of human kidney using 16806-1-AP

Immunohistochemical analysis of paraffin-embedded human kidney tissue slide using 16806-1-AP (IL1 beta antibody at dilution of 1:200 (under 10x lens).

Immunohistochemical analysis of paraffin-embedded human kidney tissue slide using 16806-1-AP (IL1 beta antibody at dilution of 1:200 (under 40x lens).

IHC staining of human tonsillitis using 16806-1-AP

Immunohistochemical analysis of paraffin-embedded human tonsillitis tissue slide using 16806-1-AP (IL1 beta antibody at dilution of 1:200 (under 10x lens). Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0).

Immunohistochemical analysis of paraffin-embedded human tonsillitis tissue slide using 16806-1-AP (IL1 beta antibody at dilution of 1:200 (under 40x lens). Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0).

IL-1 Beta Polyclonal antibody 192 Publications

Rabbit Polyclonal| Catalog number: 16806-1-AP

Tested Applications

Product Information

Immunogen Information

Background

Showing 1- [6] of [192] Publications

WB Figures

IHC Figures

IL-1 Beta Polyclonal antibody 192 Publications

Rabbit Polyclonal| Catalog number: 16806-1-AP

Related Primary Antibodies

Tested Applications

Product Information

Immunogen Information

Background